Valium less sedating than klonopin
Lorazepam is extensively conjugated to the 3- O-phenolic glucuronide in the liver and undergoes enterohepatic recirculation.88% of lorazepam is excreted in the urine (with 75% excreted as the glucuronide) and 7% in feces..
If you take Valium, you should avoid large amounts of grapefruit or grapefruit juice.These effects can happen with both drugs, so if they’re a serious concern for you, talk to your doctor about the right treatment for your anxiety.You should also never stop taking these drugs abruptly.Stopping these drugs too quickly can lead to withdrawal.Seek your doctor’s advice on the best way to stop taking these drugs slowly.Always tell your doctor and pharmacist about all drugs and supplements you currently take before you start taking any new drug.
Certain people should not take one or either of these drugs.
According to multicenter comparison lorazepam is associated with a higher risk of refractoriness and a greater number of side effects compared to the clonazepam.
The superior efficacy of clonazepam for control of status epilepticus may be at least in part because of its simpler dosing.
Grapefruit blocks the enzyme CYP3A4, which helps break down certain drugs.
So, having large amounts of grapefruit can increase the levels of Valium in your body. Xanax and Valium are in the same drug class, so they have many of the same interactions with other drugs and substances.
You shouldn’t take Xanax or Valium if you have acute angle-closure glaucoma or a history of allergic reaction to either drug.